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Effects of gender on the health and development of medically at-risk infants
June Cho1, Diane Holditch-Davis, Margaret S Miles
1School of Nursing, University of Alabama at Birmingham, Birmingham, AL 35294, USA. jcho@uab.edu
Insights
Male infants, particularly premature or HIV-positive ones, face higher risks in cognitive and motor development. Early developmental screening is crucial for these medically at-risk infants.
Area of Science:
- Pediatrics
- Developmental Psychology
- Neonatology
Background:
- Medically at-risk infants, including premature, medically fragile, and HIV-seropositive infants, require careful monitoring for health and developmental trajectories.
- Understanding gender-specific outcomes is essential for targeted interventions in vulnerable infant populations.
Purpose of the Study:
- To investigate gender-differentiated health and developmental outcomes in medically at-risk infants.
- To identify specific risk factors influencing cognitive, motor, and language development in infants.
Main Methods:
- A longitudinal descriptive and comparative secondary analysis was conducted.
- Data were collected from medical records and home visits for 108 premature, 67 medically fragile, and 83 HIV-seropositive infants.
- Developmental assessments included the Bayley Scales of Infant Development-II, Vineland Adaptive Behavior Scale, and Preschool Language Scale-3.
Main Results:
- Gender differences in health and developmental outcomes were less pronounced in medically fragile infants compared to premature and HIV-seropositive groups.
- Cognitive, motor, and language scores showed a decline with increasing age across all infant groups.
Conclusions:
- Male gender is a significant biological risk factor for cognitive and motor development, especially in premature infants.
- Early and advanced developmental screening by trained professionals is recommended for male infants born prematurely or with HIV.
Objectives:
To examine gender-differentiated health and cognitive/motor/language developmental outcomes among medically at-risk infants.
Design:
Longitudinal descriptive and comparative secondary analysis.
Setting:
Neonatal Intensive Care Unit, intermediate care unit, and infectious disease clinic of tertiary medical centers in the southeast and east United States.
Participants:
One hundred eight (108) premature infants, 67 medically fragile infants, and 83 infants seropositive for HIV.
Methods:
Neonatal and later health variables were obtained from the medical record to determine the technology dependence scores and frequency of common health problems. Data for physical growth and cognitive/motor/language development were obtained through the physical measurement, including the Bayley Scales of Infant Development-Second Edition, the Vineland Adaptive Behavior Scale, the Toll Control Developmental Checklist, and the Preschool Language Scale-3 during home visits between 6 and 27 months corrected ages.
Results:
Fewer effects on health and developmental outcomes related to gender were observed with medically fragile infants than the other two groups of infants. The cognitive/motor/language scores were decreased with increasing age of the infants in all groups.
Conclusion:
Male gender can be considered a significant biological risk factor for infants' cognitive and motor development, especially for premature infants. Because of their increased risk, it is recommended that male infants who are born prematurely or seropositive for HIV have early and advanced developmental screening tests by trained personnel through periodic pediatric clinic.
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