Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved DNA...
What is Biodiversity?01:19

What is Biodiversity?

Biodiversity describes the variety of living things at multiple organizational levels: genetic, species and ecosystem diversity. Species diversity includes all branches of the evolutionary tree from single-celled prokaryotic organisms, bacteria, and archaea, to the eukaryotic kingdoms: plants; animals; fungi; and protists. To date, there have been about 1.75 million species identified, and new species are discovered every week.
Hybrid Zones02:29

Hybrid Zones

Hybrid zones are narrow regions where two closely related species interact, mate, and produce hybrids. Relative to either parent species, hybrids may possess distinct phenotypic or genetic differences that impact their survival and reproductive success. The genetic variances introduced by hybridization influence species diversity and speciation processes within the hybrid zone.Gene flow and natural selection are evolutionary mechanisms that shape the outcome of a hybrid zone. Gene flow...
Phylogenetic Species Concept in Microbiology01:22

Phylogenetic Species Concept in Microbiology

The phylogenetic species concept (PSC) is a framework used to delineate species based on evolutionary relationships, emphasizing shared ancestry and diagnosable genetic traits. Unlike morphological or biological species concepts, the PSC is particularly advantageous for microbial taxonomy, where traditional reproductive or phenotypic criteria often fall short due to the prevalence of asexual reproduction, minimal morphological differentiation, and widespread horizontal gene transfer among...
Collisions in Multiple Dimensions: Introduction01:05

Collisions in Multiple Dimensions: Introduction

It is far more common for collisions to occur in two dimensions; that is, the initial velocity vectors are neither parallel nor antiparallel to each other. Let's see what complications arise from this. The first idea is that momentum is a vector. Like all vectors, it can be expressed as a sum of perpendicular components (usually, though not always, an x-component and a y-component, and a z-component if necessary). Thus, when the statement of conservation of momentum is written for a problem,...
Symbiosis00:58

Symbiosis

Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficient septum formation is essential for chromosome segregation in <i>Bacillus subtilis</i> when SMC function is impaired.

bioRxiv : the preprint server for biology·2026
Same author

Patient-derived organoids across cancers reveal conserved tumor heterogeneity and actionable therapeutic vulnerabilities.

Science advances·2026
Same author

The last bacterial common ancestor encoded a complex flagellum.

bioRxiv : the preprint server for biology·2026
Same author

Flagellar toxicity: flagellar synthesis is lytic for <i>Bacillus subtilis</i> in the absence of PBP1.

bioRxiv : the preprint server for biology·2026
Same author

EXaCT-2: an augmented and customizable oncology-focused whole exome sequencing platform.

NPJ precision oncology·2026
Same author

Initiation of swarming in <i>Bacillus subtilis</i> as a resolution for the sorites paradox in bacteria.

Proceedings of the National Academy of Sciences of the United States of America·2026

Related Experiment Video

Updated: Jun 8, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

Multi-species integrative biclustering.

Peter Waltman1, Thadeous Kacmarczyk, Ashley R Bate

  • 1Computer Science Department, Warren Weaver Hall (Room 305), 251 Mercer Street, New York, NY 10012, USA. waltman@cs.nyu.edu

Genome Biology
|October 6, 2010
PubMed
Summary
This summary is machine-generated.

We developed multi-species cMonkey for analyzing multiple bacterial genomes. This algorithm reveals conserved regulatory modules, offering evolutionary insights across species like Bacillus and Listeria.

Related Experiment Videos

Last Updated: Jun 8, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

Area of Science:

  • Genomics
  • Bioinformatics
  • Evolutionary Biology

Background:

  • Comparative genomics requires methods for analyzing heterogeneous datasets.
  • Understanding gene regulation across species is crucial for evolutionary insights.

Purpose of the Study:

  • To introduce multi-species cMonkey, an algorithm for simultaneous biclustering of multiple species data.
  • To apply this algorithm to bacteria, including Bacillus subtilis, Bacillus anthracis, and Listeria monocytogenes.
  • To uncover evolutionary insights into conserved regulatory modules.

Main Methods:

  • Development and application of the multi-species cMonkey algorithm.
  • Simultaneous biclustering of heterogeneous genomic data from three bacterial species.
  • Comparative analysis of regulatory module conservation.

Main Results:

  • The multi-species cMonkey algorithm successfully performed biclustering on the selected bacterial datasets.
  • Significant conservation of regulatory modules was identified across Bacillus subtilis, Bacillus anthracis, and Listeria monocytogenes.
  • The study revealed evolutionary insights supported by conserved genetic elements.

Conclusions:

  • Multi-species cMonkey is effective for comparative genomic analysis.
  • High conservation of regulatory modules exists across these bacterial species.
  • This approach facilitates cross-species data analysis, leveraging knowledge from well-studied organisms.