Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

Mesenchymal Stem Cells

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their access...

Tissue Renewal without Stem Cells

Tissue Renewal without Stem Cells

After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Borderland Hearing Health: Insights From Community-Based Screenings.

American journal of audiology·2026

Same author

SynaptoTagMe, a toolkit for in vivo mapping and modulating neurotransmission at single-cell resolution.

eLife·2026

Same author

A Moderated Mediation Model Linking Speech-in-Noise Exposure, Speech Perception in Noise Ability, Loneliness, and Depression.

Journal of speech, language, and hearing research : JSLHR·2026

Same author

Effects of hearing loss and hearing aids on environmental sound ratings in the lab and real worlda).

The Journal of the Acoustical Society of America·2026

Same author

An Evaluation of Preset Collection Size in Over-the-Counter Hearing Aids.

Ear and hearing·2026

Same author

Adipose tissue-derived mesenchymal stromal cell therapy in nonischemic heart failure with reduced ejection fraction - ARIISE study design.

Future cardiology·2026

Search research articles

Related Experiment Video

Updated: Jun 8, 2026

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue

Published on: October 8, 2016

[Cardiovascular regeneration using mesenchymal stem cells].

Anders Bruun Mathiasen¹, Mandana Haack Sørensen, Erik Jørgensen

¹Rigshospitalet, Kardiologisk Laboratorium 2014, Hjertecentret, 2100 København Ø, Denmark.

Ugeskrift for Laeger

|October 6, 2010

Summary

Mesenchymal stem cells (MSC) show promise for regenerative therapy in cardiovascular disease. Clinical studies indicate MSC treatment can improve heart function, reduce infarct size, and alleviate symptoms in patients with ischemic heart disease.

More Related Videos

In Vitro Differentiation of Human Mesenchymal Stem Cells into Functional Cardiomyocyte-like Cells

In Vitro Differentiation of Human Mesenchymal Stem Cells into Functional Cardiomyocyte-like Cells

Published on: August 9, 2017

Ultrasound-Guided Induced Pluripotent Stem Cell-Derived Cardiomyocyte Implantation in Myocardial Infarcted Mice

Ultrasound-Guided Induced Pluripotent Stem Cell-Derived Cardiomyocyte Implantation in Myocardial Infarcted Mice

Published on: March 30, 2022

Related Experiment Videos

Last Updated: Jun 8, 2026

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue

Isolation of Perivascular Multipotent Precursor Cell Populations from Human Cardiac Tissue

Published on: October 8, 2016

In Vitro Differentiation of Human Mesenchymal Stem Cells into Functional Cardiomyocyte-like Cells

In Vitro Differentiation of Human Mesenchymal Stem Cells into Functional Cardiomyocyte-like Cells

Published on: August 9, 2017

Ultrasound-Guided Induced Pluripotent Stem Cell-Derived Cardiomyocyte Implantation in Myocardial Infarcted Mice

Ultrasound-Guided Induced Pluripotent Stem Cell-Derived Cardiomyocyte Implantation in Myocardial Infarcted Mice

Published on: March 30, 2022

Area of Science:

Regenerative Medicine
Cardiovascular Research
Stem Cell Therapy

Background:

Mesenchymal stem cells (MSC) are a key focus in regenerative medicine due to their multipotent differentiation capacity.
MSC are readily isolated, cultured, and expanded in vitro, making them a practical source for therapeutic applications.
Current research explores MSC's potential to treat various conditions, particularly cardiovascular diseases.

Purpose of the Study:

To review the current status of regenerative treatment using mesenchymal stem cells (MSC) in cardiovascular disease.
To highlight the therapeutic potential and clinical findings of MSC in treating ischemic heart conditions.

Main Methods:

Review of existing clinical studies and research on MSC therapy for cardiovascular disease.
Analysis of data on left ventricular function, perfusion, infarct size, and symptom reduction.

Main Results:

Clinical trials using MSC in patients with ischemic heart disease have demonstrated positive outcomes.
Improvements observed include enhanced left ventricular function and myocardial perfusion.
Significant reductions in infarct size and associated symptoms have been reported.

Conclusions:

Mesenchymal stem cells (MSC) represent a promising therapeutic strategy for cardiovascular disease.
MSC regenerative treatment shows efficacy in improving cardiac function and reducing damage in ischemic heart conditions.
Further research and clinical application of MSC hold significant potential for advancing cardiovascular regenerative therapy.