Identified GnRH neuron electrophysiology: a decade of study
1Department of Molecular and Integrative Physiology, 7725 Med Sci II, 1301 E Catherine St., Ann Arbor, MI 48109-5622, USA. smoenter@umich.edu
Brain Research
|October 6, 2010
Abstract
None:
Over the past decade, the existence of transgenic mouse models in which reporter genes are expressed under the control of the gonadotropin-releasing hormone (GnRH) promoter has made possible the electrophysiological study of these cells. Here, we review the intrinsic and synaptic properties of these cells that have been revealed by these approaches, with a particular regard to burst generation. Advances in our understanding of neuromodulation of GnRH neurons and synchronization of this network are also discussed.


