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Drainage of Aspergillus "primitive" brain abscess with long-term survival. Case report
Abstract:
Aspergillus species are second only to Candidosis as the most common cause of fungal infections of the central nervous system in immunocompromised patients. Very rare is the sole abscessual cerebral localization in nonimmunocompromised patients. Successful treatment of Aspergillus brain abscess has been reported only few times. A case of Aspergillus "primitive" brain abscess treated by surgical therapy associated with local and general mirated antifungal therapy is described. The long-term survival with complete clinical and radiological recovery is reported.
Insights
This study reports a rare case of a primary Aspergillus brain abscess in a non-immunocompromised patient. Successful treatment involved surgery and antifungal therapy, leading to complete recovery.
Area of Science:
- Neurology
- Mycology
- Infectious Diseases
Background:
- Aspergillus species are a common cause of fungal central nervous system infections, particularly in immunocompromised individuals.
- Isolated Aspergillus brain abscesses in non-immunocompromised patients are exceedingly rare.
Observation:
- This case details a "primitive" Aspergillus brain abscess in a patient without known immune compromise.
- The abscess was treated with a combination of surgical intervention and targeted antifungal therapies, both local and systemic.
Findings:
- The patient achieved long-term survival following the treatment regimen.
- Complete clinical and radiological recovery was observed, indicating successful eradication of the infection.
Implications:
- This case highlights the possibility of successful management of rare Aspergillus brain abscesses in non-immunocompromised hosts.
- It underscores the importance of considering surgical and multimodal antifungal approaches for such challenging infections.