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Published on: May 8, 2013
Bacteriological study of pyoderma with special reference to antibiotic susceptibility to newer antibiotics
1Department of Microbiology, BJ Medical College, Pune, India.
Abstract:
Five hundred and forty-two cases of pyoderma were investigated to study bacterial aetiology and their antibiotic susceptibility patterns. Of these 65.87% cases were of primary pyoderma and the rest were of secondary pyoderma. Maximum cases were of impetigo (38.78%) followed by folliculitis (12.92%), furunculosis (2.95%), ecthyma (3.5%), carbuncle (1.5%) and sycosis barbae (0.4%). Secondary pyoderma constituted infected trophic ulcer (18.82%), infected pemphigus (7.2%), infected contact dermatitis (6.27%), and infected scabies (1.8%). Single organism was isolated from 46.9% cases and more than one type of organisms in 65.46% of cases. No organism was isolated in 5% of cases. Staphylococcus (67.34%) was the predominant species isolated followed by beta-haemolytic streptococcus (21.77%). Maximum strains of Staph. aureus were susceptible to amikacin (75%), co-trimoxazole (72%), cefotaxime (65%), chloramphenicol (62%), ciprofloxacin (61%) and clindamycin (61%). There was low susceptibility to cephaloridin (11%), gentamicin (12%) and penicillin (21%). Streptococcus betahaemolyticus was highly sensitive to most of the antibiotics and less sensitive to cefotaxime (7%), co-trimoxazole (11%) and penicillin (27%). Most of the strains were found to be resistant to one or more antibiotics.
Insights
This study investigated bacterial causes of pyoderma, finding Staphylococcus aureus and beta-hemolytic Streptococcus as common culprits. Antibiotic susceptibility testing revealed varying resistance patterns, highlighting the need for targeted treatment strategies.
Area of Science:
- Dermatology
- Microbiology
- Infectious Diseases
Background:
- Pyoderma, a common skin infection, presents as either primary or secondary forms.
- Understanding the bacterial etiology and antibiotic susceptibility is crucial for effective management.
Purpose of the Study:
- To investigate the bacterial causes of pyoderma.
- To determine the antibiotic susceptibility patterns of isolated bacteria.
Main Methods:
- A study of 542 pyoderma cases.
- Bacterial isolation and identification.
- Antibiotic susceptibility testing using various agents.
Main Results:
- Staphylococcus aureus (67.34%) and beta-hemolytic Streptococcus (21.77%) were the predominant bacteria.
- Staph. aureus showed high susceptibility to amikacin, co-trimoxazole, and cefotaxime.
- Beta-hemolytic Streptococcus exhibited sensitivity to most antibiotics but lower sensitivity to cefotaxime, co-trimoxazole, and penicillin.
- A significant proportion of bacterial strains demonstrated resistance to multiple antibiotics.
Conclusions:
- Staphylococcus aureus and beta-hemolytic Streptococcus are key pathogens in pyoderma.
- Antibiotic resistance is a growing concern, necessitating careful selection of treatments.
- Susceptibility patterns vary between bacterial species, guiding empirical therapy choices.
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