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Updated: Jun 8, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Disseminated malignant melanoma
K K Verma1, P D'Souza, C S Sirka
1Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi-110029, India.
Abstract:
A 25-year-old man had multiple asymptomatic, nodular lesions on the trunk, extremities and the face for 3 months. He also had left facial palsy with severe headache and vomiting. There were no other systemic or constitutional symptoms. Skin biopsy from a nodular lesion showed features of malignant melanoma, confirmed by Fontana Masson and S-100 protein staining. A diagnosis of disseminated malignant melanoma was made and the patient was treated symptomatically. The patient died in 4 months.
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