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Relationship between lichen planus and hepatitis C virus
S Narayan1, R C Sharma, B K Sinha
1Departments of Pathology and Dermatology, Lady Hardinge Medical College, New Delhi- 110001, India.
Indian Journal of Dermatology, Venereology and Leprology
|October 6, 2010
Summary
This study investigated the link between lichen planus and hepatitis C virus (HCV) in 75 patients. Results showed a low prevalence of HCV antibodies, similar to India's general population.
Area of Science:
- Dermatology
- Hepatology
- Epidemiology
Background:
- Lichen planus is an inflammatory condition affecting skin and mucous membranes.
- Hepatitis C virus (HCV) infection is a significant global health concern.
- Previous studies have suggested a potential association between lichen planus and HCV.
Purpose of the Study:
- To determine the seroprevalence of hepatitis C virus antibodies in patients diagnosed with lichen planus.
- To explore the relationship between lichen planus and HCV infection in the Indian population.
Main Methods:
- A cohort of 75 patients with confirmed lichen planus was recruited.
- Hepatitis C virus antibody testing was performed on all participants.
- Prevalence data was compared with existing epidemiological data for HCV in India.
Main Results:
- Only 2 out of 75 patients (2.66%) tested positive for hepatitis C virus antibodies.
- The observed HCV antibody prevalence in lichen planus patients was comparable to the general population in India (1.5%–2.2%).
Conclusions:
- The study found no significant association between lichen planus and hepatitis C virus infection in the studied cohort.
- Hepatitis C virus infection does not appear to be a major risk factor for developing lichen planus in this population.
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