Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

RIFM fragrance ingredient safety assessment, benzyl acetone, CAS Registry Number 2550-26-7.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2019
Same author

RIFM fragrance ingredient safety assessment, 1,5-dimethylhexyl acetate, CAS Registry Number 67952-57-2.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2019
Same author

RIFM fragrance ingredient safety assessment, anisyl phenylacetate, CAS Registry Number 102-17-0.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2019
Same author

RIFM fragrance ingredient safety assessment, 2-phenoxyethanol, CAS Registry Number 122-99-6.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2019
Same author

RIFM fragrance ingredient safety assessment, 2-heptanone, CAS Registry Number 110-43-0.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2019
Same author

RIFM fragrance ingredient safety assessment, propionic acid, CAS Registry Number 79-09-4.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2019
Same journal

Severe combined immunodeficiency (SCID) with pigmentary mosaicism: A coincidental occurrence in a child.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Agminated multifocal eruptive lobular capillary haemangiomas - An uncommon presentation.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Patch testing in India: Are we missing clinically relevant allergens?

Indian journal of dermatology, venereology and leprology·2026
Same journal

Double-loading technique for improved suspension retention on the recipient site in non-cultured epidermal cell suspension (NCES).

Indian journal of dermatology, venereology and leprology·2026
Same journal

Late-onset metastatic melanoma arising from a medium-sized congenital melanocytic naevus.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Custom-compounded glycine-proline jelly for ulcers in prolidase deficiency.

Indian journal of dermatology, venereology and leprology·2026
See all related articles

Related Experiment Video

Updated: Jun 8, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Granuloma faciale.

K Joshi1, S Patel, P P Shah

  • 1Department of Dermatology, Venereology and Leprology, B J Medical College and Civil Hospital, Asarwa, Ahmedabad-16, India.

Indian Journal of Dermatology, Venereology and Leprology
|October 6, 2010
PubMed
Summary
This summary is machine-generated.

Granuloma faciale is a rare skin condition presenting as a facial plaque. Treatment with oral dapsone and intralesional corticosteroids effectively improved this patient's symptoms.

Related Experiment Videos

Last Updated: Jun 8, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Area of Science:

  • Dermatology
  • Histopathology
  • Clinical Medicine

Background:

  • Granuloma faciale is a rare, benign, chronic inflammatory condition of the skin.
  • It typically presents as erythematous, infiltrated plaques, often on the face.
  • The exact etiology remains unknown, but immune system dysregulation is suspected.

Purpose of the Study:

  • To report a case of granuloma faciale in a 40-year-old woman.
  • To describe the clinical presentation and histopathological findings.
  • To evaluate the treatment response to oral dapsone and intralesional corticosteroids.

Main Methods:

  • A 40-year-old female patient presented with a long-standing asymptomatic facial plaque.
  • A skin biopsy was performed for histopathological examination.
  • Treatment was initiated with oral dapsone and intralesional corticosteroid injections.

Main Results:

  • Histopathology confirmed the diagnosis of granuloma faciale.
  • The patient showed marked clinical improvement following treatment.
  • The plaque significantly reduced in size and erythema.

Conclusions:

  • Granuloma faciale, though rare, should be considered in the differential diagnosis of persistent facial plaques.
  • A combination of oral dapsone and intralesional corticosteroids can be an effective treatment modality.
  • Early diagnosis and appropriate management are crucial for favorable outcomes in granuloma faciale.