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Trends in matrix metalloproteinase research from 1986-2007: a bibliometric study
Claude Robert1, Concepción S Wilson, Jean-François Gaudy
1Université Paris Descartes, Faculté de Chirurgie Dentaire, Laboratoire d'Anatomie Fonctionnelle, 92 120 Montrouge, France. claude.robert@parisdescartes.fr
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire
|October 6, 2010
Summary
Research on matrix metalloproteinase (MMP) expanded sevenfold from 1986-2007, with increased global participation and a shift towards clinical applications. Emerging Asian countries are now key contributors to MMP studies.
Area of Science:
- Biomedical research
- Biochemistry
- Pharmacology
Background:
- Matrix metalloproteinases (MMPs) are crucial enzymes involved in various physiological and pathological processes.
- Understanding the evolution of MMP research provides insights into scientific trends and global collaboration.
Purpose of the Study:
- To quantitatively describe the development of matrix metalloproteinase (MMP) research over a 20-year period (1986-2007).
- To analyze trends in publication output, geographical distribution, journal proliferation, and research focus.
Main Methods:
- Bibliometric analysis of scientific literature indexed in the SCI-expanded database.
- Quantitative assessment of publication numbers, participating countries, and journal distribution.
Main Results:
- MMP-related publications increased sevenfold between 1986-1987 and 2006-2007.
- Global research participation doubled, with the USA leading and emerging Asian countries (China, South Korea, Taiwan) joining the top 10.
- Research focus shifted from basic science to clinical medicine, with oncology journals gaining prominence.
Conclusions:
- MMP research has experienced significant growth and internationalization over two decades.
- The field shows a clear trend towards clinical relevance, particularly in oncology.
- Continued monitoring of research trends is essential for understanding scientific progress in MMPs.
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