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Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Bones of the Lower Limb: Femur and Patella01:16

Bones of the Lower Limb: Femur and Patella

The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the neck...
Growth of Cartilage and Bone Tissue01:27

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
Bones of the Upper Limb: Humerus01:19

Bones of the Upper Limb: Humerus

The upper limb consists of the arm, forearm, wrist, and hand bones. The humerus is the single bone of the upper arm region. Proximally, it has a large, spherical, smooth head that articulates with the glenoid cavity of the scapula to form the glenohumeral or shoulder joint. The margin of the head is the anatomical neck, a residual epiphyseal plate. Laterally it extends to form bony projections called the greater tubercle and the lesser tubercle. Next to the tubercles is the surgical neck, a...
Bones of the Lower Limb: Tibia and Fibula01:10

Bones of the Lower Limb: Tibia and Fibula

The tibia is the main weight-bearing bone of the lower leg. It is larger than the fibula with which it is paired. The tibia is also the second longest bone in the body and is located right below the skin. The proximal end of the tibia forms the medial and the lateral condyle, which articulates with the condyles of the femur to form the knee joint. Between the articulating surfaces is the irregular elevated area known as the intercondylar eminence that serves as the inferior attachment point for...
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Updated: Jun 8, 2026

Reverse Total Shoulder Arthroplasty
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Reverse Total Shoulder Arthroplasty

Published on: July 5, 2011

100 most cited articles in orthopaedic surgery.

Kelly A Lefaivre1, Babak Shadgan, Peter J O'Brien

  • 1Department of Orthopaedic Surgery, University of British Columbia, 110-828 West 10th Avenue, Vancouver, BC V5Z 1L8, Canada. kelly.lefaivre@vch.ca

Clinical Orthopaedics and Related Research
|October 6, 2010
PubMed
Summary

The most cited orthopaedic articles often introduce classification systems or outcome tools. These highly recognized works are frequently clinical and published in English, favoring those originating from specific countries.

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Last Updated: Jun 8, 2026

Reverse Total Shoulder Arthroplasty
10:10

Reverse Total Shoulder Arthroplasty

Published on: July 5, 2011

Area of Science:

  • Orthopaedic Surgery
  • Bibliometrics
  • Scientific Impact

Background:

  • Citation analysis is a key metric for recognizing influential scientific works in medicine.
  • Identifying highly cited articles helps understand the foundational knowledge within medical specialties.
  • Classic works in orthopaedics are often determined by peer recognition through citations.

Purpose of the Study:

  • To rank the top 100 most cited articles in orthopaedic journals.
  • To analyze characteristics of these highly cited articles to identify factors contributing to their importance.
  • To assess changes in the level of evidence of top-cited orthopaedic studies over time.

Main Methods:

  • Searched the Science Citation Index Expanded for articles in "ORTHOPEDICS" journals.
  • Identified the 100 most cited articles across 49 orthopaedic journals using cited reference searches.
  • Reviewed articles for publication year, country, journal, article type, and level of evidence, categorizing by research field.

Main Results:

  • The 100 most cited articles received 353 to 1748 citations.
  • These articles were published in 11 of the 49 journals, covering general and subspecialty areas.
  • The majority (76%) were clinical studies, with Level IV evidence being most common (42/76).
  • Twenty-seven clinical articles introduced or tested classification systems or outcome measurement tools.

Conclusions:

  • Highly cited orthopaedic articles are often clinical, particularly those introducing classification systems or outcome tools.
  • Factors favoring high citation include publication language (English), source journal prestige, country of origin, and the introduction of novel assessment methods.