[Autoimmunity and autoimmune syndrome: norm and pathology]

Area of Science:

• Immunology
• Preventive Medicine
• Biomarker Discovery

Context:

• Current medical approaches focus on treatment rather than prevention.
• Early detection of immune disorders is crucial for effective intervention.
• Personalized medicine requires understanding individual genetic and epigenetic factors.

Purpose:

• To explore multicomponent analysis of serum marker antibodies for early diagnosis.
• To establish antibody spectra as a basis for health prognostication.
• To facilitate a paradigm shift towards prognosis and prevention in medicine.

Summary:

• Multicomponent analysis of serum marker antibodies offers an effective method for the pre-clinical diagnosis of immune disorders.
• Studying individual antibody spectra, influenced by genetic and epigenetic features, enables health and disease prognostication.
• Early identification of reversible pathological processes can halt disease progression, preserving patient health.

Impact:

• Enables a transition to a proactive health management model.
• Potential to revise current medical diagnostic and treatment strategies.
• Empowers individuals with insights into their health trajectory based on unique biological markers.