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Updated: Jun 8, 2026

Preparation of a Corannulene-functionalized Hexahelicene by Copper(I)-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Structure-activity relationships of sandalwood odorants: synthesis of a new campholene derivative
Iris Stappen1, Joris Höfinghoff, Gerhard Buchbauer
1Department of Clinical Pharmacy and Diagnostics, University of Vienna, Vienna, Austria. Iris.Stappen@univie.ac.at
Abstract:
Structural modifications of natural (-)-(Z)-beta-santalol have shown that the sandalwood odor impression is highly sensitive, even to small structural changes. Particularly, the substitution of the quaternary carbon is of great influence on the scent. Epi-compounds with side chains in the endo-position possess sandalwood odor in only a few derivatives, whereas modifications at this side chain, as well as modification at the bicyclic ring systems mostly lead to a complete loss of sandalwood fragrance.
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