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Bacterial Gastroenteritis

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Chronic Salmonella Infection Induced Intestinal Fibrosis

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The collagenous gastroenteritides: similarities and differences.

Purva Gopal¹, Barbara J McKenna

¹Department of Pathology, University of Michigan, Ann Arbor, USA. purva.gopal@vanderbilt.edu

Archives of Pathology & Laboratory Medicine

|October 7, 2010

Summary

Collagenous gastritis, sprue, and colitis share histologic similarities and associations, but pediatric cases differ. Their shared etiologies remain unknown, questioning if they share pathogenesis or are a common response to injury.

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Area of Science:

Gastroenterology
Pathology

Background:

Collagenous gastritis, sprue, and colitis are distinct gastrointestinal disorders.
These conditions exhibit similar histological features and are sometimes diagnosed concurrently in patients.

Observation:

Collagenous gastritis, collagenous sprue, and collagenous colitis share histological similarities.
Some drug and disease associations are common across these conditions.
Pediatric collagenous gastritis cases present differently, lacking many common associations.

Findings:

The etiologies of collagenous gastroenteritides are currently unknown.
It is unclear if the similarities stem from shared pathogenesis or a common histological response to diverse injuries.

Implications:

Further research is needed to elucidate the pathogenesis of collagenous gastroenteritides.
Understanding the underlying mechanisms may lead to more targeted treatments for these conditions.