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Domain shuffling during evolution of the proteins of the bacterial phosphotransferase system
Research in Microbiology
|November 1, 1990
Abstract:
About twenty permeases of the bacterial phosphoenolpyruvate:sugar phosphotransferase system (PTS) have been sequenced and analysed. The results of these analyses suggest that interdomain shuffling, splicing, fusion, deletion, and duplication have occurred repeatedly during their evolution. A uniform nomenclature for these proteins and their domains is proposed.