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Related Concept Videos

Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
Antidepressant Drugs: Overview01:25

Antidepressant Drugs: Overview

Antidepressant drugs are a class of medications primarily used for treating various mood disorders, including major depression, anxiety disorders, and other related conditions. These medicines work by modulating the neurotransmitter balance within the brain, alleviating depressive symptoms. Antidepressants can be broadly categorized into several groups according to their mechanism of action and chemical structure: Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine...
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs01:28

Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs

Tricyclic Antidepressants (TCAs), including Desipramine (Norpramin), Imipramine (Tofranil), Clomipramine (Anafranil), and Amitriptyline (Elavil), inhibit serotonin and norepinephrine reuptake and also block other receptors. They are used for depression, pain conditions, and insomnia. Common adverse effects include anticholinergic effects, sedation, orthostatic hypotension, and weight gain. They have a narrow therapeutic window and so require plasma-level monitoring. Abrupt discontinuation can...
Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...

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Related Experiment Video

Updated: Jun 8, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

Using complementary and alternative medicines for depression.

Maurizio Fava1

  • 1Department of Psychiatry, Harvard Medical School and Massachusetts General Hospital, Boston, USA.

The Journal of Clinical Psychiatry
|October 7, 2010
PubMed
Summary
This summary is machine-generated.

Patients with psychiatric disorders increasingly use complementary and alternative medicines (CAM). Clinicians need to be informed about CAMs like omega-3 fatty acids and St. John's wort for accurate patient guidance.

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Area of Science:

  • Integrative psychiatry
  • Nutritional psychiatry
  • Evidence-based complementary medicine

Background:

  • Growing prevalence of complementary and alternative medicines (CAM) use in psychiatric care.
  • Necessity for clinicians to possess knowledge of CAM therapies for informed patient consultation.
  • Review of specific CAMs: omega-3 fatty acids, folate, SAM-e, and St. John's wort.

Discussion:

  • CAMs are frequently utilized by individuals with mental health conditions.
  • Healthcare providers require updated information on CAM efficacy and safety.
  • Clinical decision-making regarding CAM integration in psychiatric treatment plans.

Key Insights:

  • Omega-3 fatty acids, folate, SAM-e, and St. John's wort are commonly considered CAMs in psychiatry.
  • Understanding patient CAM usage is crucial for comprehensive mental healthcare.
  • Clinicians play a vital role in guiding patients on appropriate CAM use.

Outlook:

  • Further research into the efficacy and safety of specific CAMs in psychiatric populations.
  • Development of clinical guidelines for integrating evidence-based CAMs into standard psychiatric practice.
  • Enhanced patient-provider communication regarding the use of complementary therapies for mental well-being.