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Related Experiment Video

Updated: Jun 8, 2026

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo

Published on: July 1, 2013

Loaded microplasma-sprayed CaP-coated implants in vivo.

R Junker¹, P J D Manders, J Wolke

¹Department of Biomaterials, Radboud University Nijmegen Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

Journal of Dental Research

|October 7, 2010

Summary

This summary is machine-generated.

Micro-plasma sprayed (MPS) calcium phosphate (CaP) coatings on titanium implants show a favorable bone response when loaded, similar to conventional plasma-sprayed (PS) coatings. Both MPS and PS CaP coatings may enhance crestal bone maintenance compared to non-coated implants.

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Last Updated: Jun 8, 2026

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo

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Published on: July 1, 2013

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An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

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Published on: February 10, 2014

Area of Science:

Biomaterials Science
Dental Implantology
Orthopedic Research

Background:

Calcium phosphate (CaP) ceramic coatings enhance osseointegration of titanium implants.
Micro-plasma spraying (MPS) offers a novel method for CaP coating deposition.
Understanding the effect of functional loading on MPS CaP-coated implants is crucial for clinical application.

Purpose of the Study:

To evaluate the bone response to titanium implants with different CaP coating methods (MPS, aMPS, PS) under functional loading.
To compare the efficacy of MPS CaP coatings with conventional PS coatings and non-coated implants.
To assess the impact of loading on crestal bone maintenance around coated and non-coated implants.

Main Methods:

Development of micro-plasma spray equipment for CaP coating.
Surgical insertion of 56 titanium implants (NC, PS, MPS, aMPS) into beagle dog mandibles.
Application of functional load to implants after 6 weeks, with a 52-week healing period.

Main Results:

Bone healing was comparable across all tested surfaces, regardless of loading.
Loading of MPS CaP-coated implants resulted in a favorable bone response, comparable to PS CaP-coated implants.
PS and MPS CaP-coated implants showed potential for increased crestal bone maintenance compared to non-coated implants.

Conclusions:

Micro-plasma sprayed calcium phosphate coatings elicit a favorable bone response upon functional loading.
The bone response to MPS CaP coatings is comparable to conventional plasma-sprayed coatings.
Functional loading of both PS and MPS CaP-coated implants may improve crestal bone preservation.