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Published on: March 15, 2022
Antiplatelet therapy in acute coronary syndromes
Krishna G Aragam1, Deepak L Bhatt
1University of Michigan, Ann Arbor, MI, USA.
Abstract:
Antiplatelet therapy is integral to the acute and long-term management of acute coronary syndromes (ACSs) and for minimizing the thrombotic complications of percutaneous coronary intervention (PCI). This article reviews the most commonly used antiplatelet agents in ACS therapy--aspirin, adenosine diphosphate (ADP)-receptor blockers, and glycoprotein IIb/IIIa inhibitors. More recent data are also reviewed on novel ADP-receptor blockers and thrombin inhibitors before addressing issues of adherence to antiplatelet regimens.
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