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Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
Published on: October 6, 2016
Aging, human immunodeficiency virus, and bone health
1Division of Orthodontics, Department of Developmental and Surgical Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN 55455, USA. kmansky@umn.edu
Clinical Interventions in Aging
|October 7, 2010
Summary
Highly active antiretroviral therapy (HAART) improves HIV prognosis but can affect bone health in aging patients. Further research is needed to understand HIV and HAART
Area of Science:
- Gerontology
- Virology
- Bone Metabolism
Background:
- Highly active antiretroviral therapy (HAART) has significantly improved human immunodeficiency virus (HIV) patient outcomes.
- A growing population of HIV-infected individuals are aging, with many now over 50 years old.
- Both HIV infection and HAART components are associated with increased noninfectious complications, including compromised bone health.
Purpose of the Study:
- To conduct a detailed mechanistic analysis of bone health risks in aging HIV-infected individuals.
- To elucidate the specific roles of HIV infection and HAART components in bone health deterioration.
- To identify preventative strategies for maintaining bone health in this population.
Main Methods:
- Mechanistic analysis of aging HIV-infected individuals.
- Review of clinical studies on noninfectious complications.
- Investigation into the impact of HAART components on bone health.
Main Results:
- HIV infection and HAART increase the risk of noninfectious complications.
- Bone health is a significant concern for aging HIV-infected individuals.
- Specific mechanisms linking HIV, HAART, and bone loss require further elucidation.
Conclusions:
- Aging HIV-infected individuals face elevated risks to bone health due to infection and treatment.
- Understanding the underlying mechanisms is crucial for developing targeted interventions.
- Preventative measures are essential for this aging demographic to maintain skeletal integrity.
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