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Updated: Jun 8, 2026
08:34
Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment
Published on: March 2, 2016
Human anelloviruses and the central nervous system
Fabrizio Maggi1, Mauro Bendinelli
1Virology Section and Retrovirus Centre, Department of Experimental Pathology, University of Pisa, Italy.
Reviews in Medical Virology
|October 7, 2010
Summary
Torque teno viruses (TTVs) cause chronic infections with high viraemia. This review explores their interactions with the central nervous system (CNS) and potential disease impacts, highlighting knowledge gaps.
Area of Science:
- Virology
- Immunology
- Neuroscience
Background:
- Torque teno viruses (TTVs) are widespread anelloviruses causing chronic human infections.
- High plasma viraemia is a hallmark of TTV infections.
- The natural history and pathogenesis of TTVs remain largely unknown.
Purpose of the Study:
- To review the general properties of anelloviruses.
- To summarize current knowledge on TTV interactions with the central nervous system (CNS).
- To discuss potential pathological consequences of TTVs in the CNS.
Main Methods:
- Literature review of existing studies on anelloviruses and TTVs.
- Analysis of reported interactions between TTVs and CNS tissues.
- Synthesis of data on TTV pathogenesis and clinical manifestations.
Main Results:
- Anelloviruses exhibit diverse genetic and biological characteristics.
- Evidence suggests TTVs can infect or interact with the CNS.
- The precise role of TTVs in CNS diseases requires further investigation.
Conclusions:
- TTVs represent a significant, yet understudied, group of human viruses.
- Understanding TTV-CNS interactions is crucial for assessing their pathological relevance.
- Further research is needed to elucidate TTV pathogenesis and clinical implications.
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