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Updated: Jun 8, 2026
09:57
Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
17-year-old girl with headache and complex partial seizure
Eun Kyung Park1, Yun-Ho Lee, Dong-Seok Kim
1Department of Neurosurgery, Severance Hospital, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
Brain Pathology (Zurich, Switzerland)
|October 8, 2010
Summary
This study details a rare supratentorial extraaxial cortical anaplastic ependymoma in a teenage girl. Despite gross total resection, adjuvant radiation therapy was administered due to aggressive histological features.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Pathology
Background:
- Ependymomas typically arise from the ventricular system or spinal cord's central canal.
- Supratentorial cortical ependymomas are exceptionally rare, with only 14 cases previously reported.
- This case represents a unique instance of an extraaxial cortical ependymoma with minimal cortical attachment.
Observation:
- A 17-year-old female presented with headache and complex partial seizures.
- Imaging revealed a supratentorial extraaxial mass with minimal cortical attachment.
- Histopathological examination showed features of anaplasia, including numerous mitoses, necrosis, and a high Ki-67 proliferation index.
Findings:
- The patient underwent gross total resection of the anaplastic ependymoma.
- Postoperative adjuvant radiation therapy was recommended due to the tumor's aggressive characteristics.
- This represents the first reported case of supratentorial extraaxial cortical anaplastic ependymoma.
Implications:
- Highlights the importance of considering rare tumor entities in neuro-oncology diagnostics.
- Emphasizes the need for multimodal treatment strategies in aggressive ependymomas.
- Contributes to the limited literature on supratentorial cortical ependymomas, aiding future research and clinical management.
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