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Mixed venous versus central venous oxygen saturation in patients undergoing on pump beating coronary artery bypass

Ahmad Alshaer1, Mohamed Essam Abdel-Meguid, Osama Ibraheim

  • 1Cardiac Anesthesia Division, King Fahad Cardiac Center, Riyadh, Saudi Arabia.

Saudi Journal of Anaesthesia
|October 8, 2010
PubMed

Insights

Central venous oxygen saturation (ScvO(2)) and mixed venous oxygen saturation (SvO(2)) are not numerically interchangeable in patients undergoing on-pump beating coronary artery bypass grafting (CABG). ScvO(2) can indicate trends but should not replace SvO(2) for absolute values.

Area of Science:

  • Cardiovascular Surgery
  • Anesthesiology
  • Critical Care Medicine

Background:

  • Central venous oxygen saturation (ScvO(2)) is often used as a surrogate for mixed venous oxygen saturation (SvO(2)).
  • The interchangeability of ScvO(2) and SvO(2) during normothermic on-pump beating coronary artery bypass grafting (CABG) requires investigation.

Purpose of the Study:

  • To evaluate the validity of using ScvO(2) as a numerical substitute for SvO(2) in adult patients undergoing CABG.
  • To determine if ScvO(2) measurements correlate with SvO(2) during different phases of the surgery.

Main Methods:

  • A prospective observational study included 34 adult patients undergoing CABG.
  • Pulmonary artery catheters were used for simultaneous measurement of SvO(2) and ScvO(2) at multiple time points.
  • Measurements were taken pre-bypass, during cardiopulmonary bypass, and post-operatively in the ICU.

Main Results:

  • ScvO(2) consistently showed higher readings than SvO(2) throughout the study.
  • A statistically significant positive correlation was observed between SvO(2) and ScvO(2).
  • The mean difference between ScvO(2) and SvO(2) was statistically insignificant pre-bypass but became highly significant during and after cardiopulmonary bypass.

Conclusions:

  • ScvO(2) and SvO(2) are not numerically interchangeable in patients undergoing on-pump beating CABG.
  • ScvO(2) is valuable for monitoring trends in oxygen saturation.
  • ScvO(2) may be used for clinical decision-making when absolute SvO(2) values are not critical.
Abstract

Keywords:
Coronary artery bypass graftingcentral venous oxygen saturationcoronary artery bypass graftingmixed venous oxygen saturation

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