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Updated: Jun 8, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Complications associated with left ventricular puncture
Sridevi R Pitta1, Allison K Cabalka, Charanjit S Rihal
1Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA.
Insights
Percutaneous left ventricular apical puncture (LVAP) is linked to significant access site complications, especially during interventions. Safer closure methods are needed for this cardiac procedure.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Percutaneous left ventricular apical puncture (LVAP) is rarely used for hemodynamic assessment with prosthetic valves.
- LVAP is increasingly utilized for complex interventions like paravalvular leak closure, often requiring larger sheaths (4-6 F).
- Optimal techniques and outcomes for LVAP with larger sheaths remain largely uncharacterized.
Purpose of the Study:
- To evaluate the complication rates associated with percutaneous left ventricular apical puncture (LVAP) and sheath placement.
- To compare complication incidence between diagnostic and interventional LVAP procedures.
- To identify the need for improved methods for managing LVAP access sites.
Main Methods:
- Retrospective analysis of 32 patients undergoing LVAP with echocardiographic and fluoroscopic guidance (2002-2009).
- Patients underwent LVAP for hemodynamic assessment or paravalvular leak closure.
- Access site complications were recorded; no specific closure devices were used for hemostasis.
Main Results:
- Access site complications were higher in interventional LVAP (25%) compared to diagnostic procedures (12.5%).
- Hemothorax was the most frequent serious complication, occurring in 19% of patients and often requiring intervention (16%).
- Three patients experienced local bleeding without significant sequelae.
Conclusions:
- Percutaneous left ventricular apical puncture (LVAP) is associated with a notable rate of access-related complications.
- There is a clear need for the development of safe and effective closure techniques for LVAP access sites.
Objective:
To report complications in a consecutive series of patients undergoing percutaneous left ventricular apical puncture (LVAP) and sheath placement for diagnostic or interventional procedures.
Background:
Percutaneous LVAP is only rarely used to provide hemodynamic data in the presence of mechanical prosthetic valves. Recently, LVAP has been used to facilitate complex interventional procedures such as paravalvular leak closures. These frequently necessitate placement of 4-6 F sheaths, rather than smaller needles. Optimal technique and outcomes are largely unknown for this uncommon procedure.
Methods:
We retrospectively analyzed 32 patients undergoing LVAP with echocardiographic and fluoroscopic guidance at our institution between 2002 and 2009. These patients were referred to the cardiac catheterization laboratory for hemodynamic assessment to rule out prosthetic dysfunction and or to facilitate paravalvular leak closure. Sheaths ranged from 4 to 6 F were removed at the end of the procedure after reversing any anticoagulation. No specific closure devices were used for hemostasis. Frequency of access site complications associated with LVAP recorded.
Results:
Apical access site related complications were higher in patients requiring LVAP for intervention than for diagnostic purposes (25% vs. 12.5%). Hemothorax was the most frequent serious complication occurring in 6 (19%) patients and frequently required intervention 5(16%). Three patients had local bleeding with no drop in hemoglobin or need for intervention.
Conclusions:
LVAP is associated with a significant incidence of access-related complications. There is a need for safe and reliable methods of closing percutaneous LVAP access sites.
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