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Published on: April 2, 2018
Enantiomer self-disproportionation and chiral stationary phase based selective chiral separation of organic compounds
Vishal J Mayani1, Sayed H R Abdi, Suranjana V Mayani
1Department of Chemical Engineering, Hoseo University, Asan-city, Choongnam, Republic of Korea.
Abstract:
In modern chromatography, chiral stationary phase (CSP) and enantiomer self-disproportionation (ESD) are new inventions of packing material offer a guarantee for a successful enantiomeric separation. All CSPs were synthesized by chemical bonding of the relevant organic moieties onto a porous parent silica material for the separation of various racemic mixtures whereas achiral silica matrix was used for separation of non-racemic mixtures in ESD. Our present study provides to establish an understanding on the entire enantio-selective profile of amino alcohol based CSP as well as ESD and their precise utilization for high success rates for selective enantiomer separation with its appropriateness.
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