Related Experiment Video
Updated: Jun 8, 2026

Development of a Neonatal Rat Model for Brachial Plexus Birth Injury
Published on: March 27, 2026
Modified C7 neurotization for the treatment of obstetrical brachial plexus palsy
Haodong Lin1, Chunlin Hou, Desong Chen
1Department of Orthopedic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai, People's Republic of China.
Insights
Contralateral C7 transfer effectively restored motor and sensory function in infants with obstetrical brachial plexus palsy (OBPP). This surgical technique shows promising results for nerve reconstruction in affected infants.
Area of Science:
- Pediatric Surgery
- Neurosurgery
- Orthopedic Surgery
Background:
- Obstetrical brachial plexus palsy (OBPP) can lead to significant functional deficits in infants.
- Nerve reconstruction techniques are crucial for improving outcomes in OBPP.
- Contralateral C7 transfer is an underutilized but potentially effective surgical option.
Purpose of the Study:
- To evaluate the efficacy of contralateral C7 transfer to two recipient nerves in infants with OBPP.
- To assess the functional recovery of motor and sensory pathways after this neurotization technique.
Main Methods:
- A modified C7 neurotization technique was used for nerve reconstruction in 9 infants with brachial plexus root avulsions.
- The contralateral C7 root was transferred to both the musculocutaneous and median nerves on the affected side.
- Patient outcomes were assessed based on muscle strength (Medical Research Council scale) and sensory function gains.
Main Results:
- Significant improvement in biceps muscle strength (M3 or M4) was observed in 7 out of 9 patients.
- Regained motor function and strength in wrist and finger flexors (M3 or M4) occurred in 5 patients following median nerve transfer.
- All patients demonstrated notable gains in sensory function.
Conclusions:
- Contralateral C7 transfer to two recipient nerves is a feasible and efficient surgical approach for infants with OBPP.
- This technique offers a viable option for restoring both motor and sensory functions in affected infants.
- Further research can explore long-term outcomes and refine surgical protocols for OBPP management.
Abstract:
Contralateral C7 transfer is used rarely in infants with obstetrical brachial plexus palsy (OBPP). We aimed to determine the efficacy of contralateral C7 transfer to two different recipient nerves in infants with OBPP. Between 2001 and 2005, 9 infants with brachial plexus root avulsions underwent nerve reconstruction using a modified C7 neurotization technique. In this procedure, the contralateral C7 root was transferred to both the musculocutaneous nerve and the median nerve on the affected side. The strength of the biceps muscles increased to M3 or M4 in 7 patients and to M2 in 2 patients. The median nerve transfers led to regained motor function and strength of wrist and finger flexors with improvement to M3 or M4 in 5 patients. All patients showed notable gains of sensory function. Contralateral C7 transfer to two different recipient nerves is a feasible and efficient approach in infants with OBPP.
