Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Atherosclerosis I: Introduction01:30

Atherosclerosis I: Introduction

Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Thoracic Aorta01:15

Thoracic Aorta

The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of IL-1 blockers on exertional leg pain in familial Mediterranean fever patients: an exploratory study.

Rheumatology (Oxford, England)·2026
Same author

A single dose of anakinra for arresting familial Mediterranean fever attacks: a proof-of-concept study.

Clinical and experimental rheumatology·2025
Same author

Non-canonical manifestations of FMF in homozygous M694V MEFV genotype: Insights from a large patient cohort.

Seminars in arthritis and rheumatism·2025
Same author

Renal outcomes and survival in amyloidosis associated with familial Mediterranean fever: A longitudinal study.

Seminars in arthritis and rheumatism·2025
Same author

Diagnostic Challenges and Solutions in Systemic Amyloidosis.

International journal of molecular sciences·2023
Same author

Screening for Fabry's disease in a high-risk subpopulation of FMF.

European journal of medical research·2022

Related Experiment Video

Updated: Jun 8, 2026

An Approach to Point-Of-Care Ultrasound Evaluation of the Abdominal Aorta
07:12

An Approach to Point-Of-Care Ultrasound Evaluation of the Abdominal Aorta

Published on: September 8, 2023

[Aortic atheroma and splenic emboli].

Itan Ben-Zvi1, Alexey Naimushin, Avi Livneh

  • 1Department of Medicine F, Sheba Medical Center, Tel Hashomer, Israel. ibenzvi@gmail.com

Harefuah
|October 9, 2010
PubMed
Summary
This summary is machine-generated.

Atheroma of the thoracic aorta can cause systemic emboli. Optimal prevention strategies remain controversial, necessitating individualized treatment based on plaque characteristics and patient risk factors.

More Related Videos

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Related Experiment Videos

Last Updated: Jun 8, 2026

An Approach to Point-Of-Care Ultrasound Evaluation of the Abdominal Aorta
07:12

An Approach to Point-Of-Care Ultrasound Evaluation of the Abdominal Aorta

Published on: September 8, 2023

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Area of Science:

  • Cardiovascular Medicine
  • Neurology
  • Vascular Surgery

Background:

  • The link between thoracic aortic atheroma and systemic embolization was recognized with advancements in transesophageal echocardiography.
  • Secondary prevention of recurrent emboli from aortic plaques lacks definitive treatment guidelines.

Observation:

  • A case study of a patient with splenic infarct caused by a mobile plaque in the descending aorta is presented.
  • The clinical presentation and diagnostic findings are detailed.

Findings:

  • Mobile aortic plaques are a source of systemic embolization to various organs.
  • Current evidence for optimal secondary prevention is conflicting, with differing study outcomes.

Implications:

  • Individualized treatment approaches are crucial due to the absence of conclusive randomized trials.
  • Treatment decisions should consider plaque morphology, patient risk factors, and available surgical and medical options.