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Published on: January 29, 2014
[Pathologic findings in auditory brain stem evoked potentials in 10 children with brain stem tumors]
J Kraus1, M Lehovský, M Procházková
1Dĕtská neurologická klinika FNsP, Praha-Motol.
Insights
Brain stem acoustic evoked potentials (BAEP) effectively detect posterior fossa tumors in children. Analyzing wave intervals aids in localizing lesions and assessing brain stem involvement.
Area of Science:
- Neuroscience
- Pediatric Oncology
- Audiology
Context:
- Posterior cranial fossa tumors in children can significantly impact neurological function.
- Brain stem acoustic evoked potentials (BAEP) are a non-invasive electrophysiological test.
Purpose:
- To evaluate the utility of BAEP in diagnosing and localizing posterior cranial fossa tumors in pediatric patients.
- To assess the sensitivity of BAEP components in identifying brain stem and cerebellar involvement.
Summary:
- Brain stem acoustic evoked potentials (BAEP) were analyzed in 10 children (2-14 years) with posterior cranial fossa tumors.
- Abnormal findings included delayed latencies, rostral component generation, and absent waves in severe cases.
- BAEP aided in lesion lateralization in 9 patients and revealed bilateral abnormalities of wave V in 8.
Impact:
- BAEP serves as a valuable tool for the diagnosis and management of pediatric posterior cranial fossa tumors.
- Inter-wave interval assessment is crucial for determining lesion site and severity.
- This study highlights the role of electrophysiology in pediatric neuro-oncology.
Abstract:
The authors examined brain stem acoustic evoked potentials (BAEP) in 10 children aged 2-14 years with tumours in the posterior cranial fossa infiltrating the cerebellum and brain stem. The tumours were diagnosed by computed tomography and in eight patients confirmed on operation. For stimulation a monaural click was used. The authors assessed the latency of waves, intervals between and investigated the presence of waves and evaluated their amplitudes. They compared the results with normal values. In abnormal findings the latency of components was delayed, the components were generated in a rostral manner from the site of the lesion in all children. In four patients with severe affections of the brain stem the investigated components were lacking. In nine patients the BAEP evoked by monaural stimulation helped to asses the lateralization of the lesion. In eight patients a bilateral abnormality of the V wave was recorded. The most sensitive indicator for assessment of the site of the lesion was assessment of the interval between two consecutive waves.
