Systolic time intervals as indicators for cardiac function in rat models for heart failure
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Echocardiographic Approaches and Protocols for Comprehensive Phenotypic Characterization of Valvular Heart Disease in Mice
Published on: February 14, 2017
1Department of Pharmacology, University of Limburg, Maastricht, The Netherlands.
Abstract:
Measurement of the pre-ejection period (PEP) can give valuable information on myocardial function in rats. Depressed cardiac function is accompanied by prolongation of PEP, which shortens when cardiac function improves. Left ventricular ejection time (LVET) may be shortened with ageing in spontaneously hypertensive rats.
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