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Updated: Jun 8, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
What's new in skin resurfacing and rejuvenation?
E B Kirkland1, H B Gladstone, B M Hantash
1Division of Dermatologic Surgery, Department of Dermatology, Stanford University Medical Center, Stanford, CA, USA.
Abstract:
Skin resurfacing and rejuvenation techniques have experienced significant advances in the last few decades, and new devices are continuously being introduced into the marketplace. The large number of available modalities such as fractional lasers, radiofrequency systems, microdermabrasion, laser-assisted lipolysis, and ultrasound provides practitioners with a wide array of choices to address the needs of cosmetic patients. Many of the newer technologies, such as devices that integrate a fractional delivery system, provide excellent results with few adverse side effects. However, proper perioperative management is essential to achieving the desired effects. Furthermore, practitioners must be fluent with the operation and expected complications of these new technologies. While there are many overlapping treatment indications for each of the devices mentioned above, some modalities offer distinct advantages making proper patient selection essential. In certain cases, utilizing various combinations of mechanical, optic, acoustic, and electrical energies may be necessary to achieve the desired outcomes. This review discusses the application of new and existing skin rejuvenation techniques to clinical practice. A particular emphasis is placed on the use of fractional, radiofrequency, microdermabrasion, laser-assisted lipolysis, and ultrasound devices.
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