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Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
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Gramene database: a hub for comparative plant genomics.

Pankaj Jaiswal1

  • 1Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR, USA.

Methods in Molecular Biology (Clifton, N.J.)
|October 9, 2010
PubMed
Summary
This summary is machine-generated.

Gramene is a powerful database integrating diverse plant genomic data for cereals and model plants. It aids researchers in exploring gene functions and interactions to understand plant development and agronomic traits.

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Area of Science:

  • Genomics
  • Bioinformatics
  • Plant Biology

Background:

  • The completion of the rice genome sequencing project and existing genetic information offer tools for studying plant agronomic traits.
  • Genomic colinearity and comparative genomics are crucial for understanding plant genomes.
  • Databases are essential for integrating and exploring vast amounts of genetic and genomic data.

Purpose of the Study:

  • To introduce Gramene, a comprehensive database for plant genomic studies.
  • To highlight Gramene's utility in exploring genomic colinearity and comparative genomics.
  • To demonstrate how Gramene facilitates research across various plant science disciplines.

Main Methods:

  • Assimilation of publicly available data from diverse cereal crops (rice, sorghum, maize, etc.), grape, poplar, and Arabidopsis.
  • Reanalysis and integration of data into knowledge domains including maps, markers, genes, proteins, pathways, phenotypes, Quantitative Trait Loci (QTL), and genetic diversity.
  • Utilizing genomic colinearity and comparative genomics for data exploration.

Main Results:

  • Gramene provides a unified platform for accessing and analyzing integrated genomic data for multiple plant species.
  • The database enables researchers to investigate gene roles, genomic organization, and interactions regulating plant development.
  • Examples from rice illustrate the database's application in diverse research areas.

Conclusions:

  • Gramene serves as a valuable resource for researchers in plant biology, breeding, genomics, and related fields.
  • The database facilitates deciphering interactions within biological systems and their role in plant development.
  • Comparative genomics and integrated data analysis through Gramene advance our understanding of plant agronomic traits.