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Updated: Jun 8, 2026

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Large-Scale Multi-Omics Genome-Wide Association Studies (Mo-GWAS): Guidelines for Sample Preparation and Normalization
Published on: July 27, 2021
[Strategies of the study on herb genome program]
Shi-lin Chen1, Yong-zhen Sun, Jiang Xu
1Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China. slchen@implad.ac.cn
Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|October 12, 2010
Summary
The Herb Genome Program (HerbGP) employs whole genome sequencing and omics methods for medicinal plants. This initiative advances traditional Chinese medicine research and natural product development.
Area of Science:
- Genomics
- Bioinformatics
- Medicinal Plant Research
Context:
- Focus on medicinal plants with unique secondary metabolism pathways.
- Importance of medical and pharmaceutical value in species selection.
Purpose:
- Systematically discuss the strategy of the Herb Genome Program (HerbGP).
- Outline the workflow from species selection to post-genomics research.
- Integrate omics methods into medicinal plant studies.
Summary:
- HerbGP utilizes whole genome sequencing (WGS) and post-genomics approaches for key medicinal plants.
- The program covers species selection, WGS, assembly, bioinformatics, and subsequent research.
- Emphasizes plants with unique secondary metabolism or significant medical value.
Impact:
- Elevates the study of Chinese traditional medicines to the forefront of life sciences.
- Positions China for leadership in traditional Chinese medicine basic research.
- Facilitates natural medicine R&D and medicinal farming through metabolic pathway analysis and cultivar selection.

