[Potential treatment of infertility with second ejaculate]

Area of Science:

• Andrology
• Reproductive Medicine
• Sperm Analysis

Background:

• Semen quality is crucial for male fertility.
• Suboptimal semen parameters affect conception rates.
• The impact of serial ejaculates on semen quality is not fully understood.

Purpose of the Study:

• To evaluate changes in sperm parameters after obtaining a second ejaculate within 60 minutes.
• To compare these changes across different baseline seminal quality groups.

Main Methods:

• Infertile patients provided a second semen sample within 1 hour of the first.
• Patients were selected based on poor semen volume, density, motility, or total motile sperm count.
• Participants were categorized into subgroups: hypospermia, oligospermia, asthenospermia, and teratospermia.

Main Results:

• A second ejaculate significantly improved sperm parameters in patients with asthenospermia (low motility) and oligospermia (low sperm count).
• A beneficial effect was also observed in patients with a total motile sperm count below 10 million.
• No significant benefit was noted for hypospermia or teratospermia groups.

Conclusions:

• A second ejaculate sample can be a valuable diagnostic and potentially therapeutic tool for specific infertile patients.
• It offers an alternative strategy for couples seeking spontaneous pregnancy or requiring assisted reproductive techniques.
• Consideration of a second sample is recommended for infertile men with asthenospermia, oligospermia, or very low total motile sperm counts.