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[Olfactory and gustatory sweating--case report on reflex facial hyperhidrosis].
B Stier1, T Schröder, H J Matschke
1Neurologische Klinik, Zentralklinik für Psychiatrie und Neurologie Wilhelm Griesinger Berlin.
Psychiatrie, Neurologie, Und Medizinische Psychologie
|November 1, 1990
Summary
This study reports a rare case of localized hyperhidrosis, specifically pathological gustatory and olfactory sweating, mimicking Frey syndrome. It proposes a new model for delayed symptom onset after nerve injury, involving central reflex pathway adjustments.
Area of Science:
- Neurology
- Dermatology
- Physiology
Background:
- Localized hyperhidrosis, particularly gustatory and olfactory sweating, is a rare vegetative disorder.
- The Frey syndrome, characterized by sweating and flushing of the face during gustatory stimulation, is a known example of reflex hyperhidrosis.
Observation:
- A case study detailing pathological gustatory and olfactory sudation with symptom progression consistent with Frey syndrome is presented.
- The observed symptoms followed a peripheral nerve lesion, suggesting a link between nerve injury and the development of hyperhidrosis.
Findings:
- A novel model is proposed to explain the delayed manifestation of symptoms after peripheral nerve injury.
- This model suggests that a readjustment of reflex excitation levels, influenced by altered peripheral afference, leads to central decompensation and pathological reflex enhancement.
- Peripheral efferent denervation hypersensitivity alone is deemed insufficient to explain the delayed onset or the classic Frey syndrome.
Implications:
- The findings challenge existing theories on the pathophysiology of Frey syndrome and related disorders.
- The proposed model offers a new framework for understanding the neuro-regulatory mechanisms underlying reflex hyperhidrosis.
- Further research into central control mechanisms of autonomic reflexes is warranted to explore therapeutic strategies for localized hyperhidrosis.