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Related Concept Videos

Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...

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Related Experiment Video

Updated: Jun 8, 2026

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma
05:22

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Published on: February 13, 2026

Cholangiocarcinoma: an endoscopist's perspective.

Muslim Atiq1, Milind Javle, Shyam Dang

  • 1Divison of Gastroenterology, Hepatology and Nutrition, MD Anderson Cancer Center, Houston, TX, USA.

Expert Review of Gastroenterology & Hepatology
|October 12, 2010
PubMed
Summary

Cholangiocarcinoma (bile duct cancer) incidence is increasing, posing diagnostic challenges. Early detection via advanced endoscopic techniques and imaging, alongside targeted therapies, is crucial for improved outcomes and palliation.

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Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
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Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

Area of Science:

  • Gastroenterology and Hepatology
  • Oncology
  • Diagnostic Imaging

Background:

  • Cholangiocarcinoma incidence is rising globally.
  • Increased detection may be due to advanced endoscopic imaging.
  • These bile duct cancers present significant diagnostic challenges.

Purpose of the Study:

  • To review the diagnostic and therapeutic landscape of cholangiocarcinoma.
  • To highlight the role of endoscopic modalities and imaging in diagnosis and staging.
  • To discuss current and emerging treatment strategies.

Main Methods:

  • Review of current literature on cholangiocarcinoma diagnosis and management.
  • Emphasis on endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS).
  • Discussion of imaging modalities for tumor extent and metastasis evaluation.

Main Results:

  • A high index of suspicion, serum markers, and endoscopic techniques are vital for diagnosis.
  • Imaging is critical for assessing resectability and detecting metastasis.
  • Surgical resection remains the primary curative option.

Conclusions:

  • Multimodality approaches involving endoscopy and imaging are essential for cholangiocarcinoma management.
  • Limited but promising therapeutic options include novel chemotherapies and targeted therapies.
  • Endoscopic interventions play a key role in palliative care.