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Updated: Jun 8, 2026

Inspiratory Muscle Training as an Adjunct to the Treatment of Weaning Failure in Critically Ill Patients: A Practical Guide
Published on: January 30, 2026
Breathing evaluation and retraining as an adjunct to manual therapy
Laurie McLaughlin1, Charlie H Goldsmith, Kimberly Coleman
1School of Rehabilitation Science, McMaster University, Hamilton, ON, Canada. laurie@proactivehealth.ca
Low End Tidal CO₂ (ETCO₂) indicates breathing dysfunction in patients with chronic back and neck pain. Breathing retraining significantly improved pain and function in these individuals, suggesting capnography screening for better manual therapy outcomes.
Area of Science:
- Physiology
- Manual Therapy
- Pain Management
Background:
- Back and neck pain are prevalent, often treated with manual therapy.
- A link exists between breathing difficulties and back pain.
- Trunk muscles serve dual roles in posture and respiration, suggesting functional interdependence.
Purpose of the Study:
- To investigate the relationship between breathing dysfunction and persistent back/neck pain.
- To evaluate the efficacy of breathing retraining in patients unresponsive to conventional manual therapy.
Main Methods:
- A case series of 29 outpatients with neck or back pain was analyzed.
- Patients with plateaued manual therapy outcomes were screened for breathing dysfunction using capnography to measure End Tidal CO₂ (ETCO₂).
- Breathing retraining was implemented as an intervention.
Main Results:
- All patients identified with low ETCO₂ (indicating breathing dysfunction) experienced improvements.
- Breathing retraining led to enhanced ETCO₂, reduced pain, and improved function.
- 93% of patients achieved clinically significant improvements in pain or function.
Conclusions:
- Low ETCO₂ is a potential indicator of breathing dysfunction in patients with chronic back and neck pain.
- Screening for breathing dysfunction via capnography may enhance manual therapy outcomes.
- Breathing retraining offers a viable adjunct treatment for patients with persistent pain unresponsive to standard care.
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