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Published on: April 15, 2021
Bilateral giant cavernous carotid artery aneurysms in a child with juvenile Paget's disease
Tausif Rehman1, Rushna Ali, Christopher Taylor
1Department of Neurosurgery, University of New Mexico, Albuquerque, New Mexico, USA. rehman@salud.unm.edu
Insights
Juvenile Paget disease (JPD) is a rare disorder. This report details the first case of JPD with bilateral giant carotid artery aneurysms, successfully treated with bypass and occlusion.
Area of Science:
- Vascular Surgery
- Genetics
- Neurology
Background:
- Juvenile Paget disease (JPD) is a rare genetic disorder affecting bone, immune, and vascular systems.
- This report presents the first documented association of JPD with bilateral giant cavernous carotid artery aneurysms in a pediatric patient.
Observation:
- A child with JPD presented with abducens nerve palsy.
- Imaging revealed bilateral giant cavernous carotid artery aneurysms.
Findings:
- The patient underwent successful bilateral superficial temporal artery to middle cerebral artery bypass and endovascular carotid artery occlusion.
- The patient experienced an event-free recovery with no new neurological deficits.
Implications:
- This case highlights a previously unreported association between JPD and giant cavernous carotid aneurysms.
- Optimal management strategies for this rare subgroup require further investigation.
- Understanding JPD pathophysiology is crucial for managing associated vascular complications.
Background:
Juvenile Paget disease (JPD) is a rare genetic bone disorder, also affecting the immune and vascular systems. We describe the first ever case of JPD associated with bilateral giant cavernous carotid artery aneurysms in a child.
Case Description:
A child with known JPD presented with left abducens nerve palsy and a computed tomographic angiogram revealed bilateral giant cavernous carotid artery aneurysms. He underwent a left-sided superficial temporal artery to middle cerebral artery bypass and endovascular carotid artery occlusion, followed by an identical procedure on the right side 3 months later and made an event-free recovery without any new neurological deficits.
Conclusions:
This previously unreported association poses the question of determining the optimal management strategy for such cases. The pathophysiology and clinical features of JPD are discussed, with special emphasis on the management of giant cavernous carotid aneurysms in this subgroup of individuals.
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