Bilateral giant cavernous carotid artery aneurysms in a child with juvenile Paget's disease

Tausif Rehman1, Rushna Ali, Christopher Taylor

  • 1Department of Neurosurgery, University of New Mexico, Albuquerque, New Mexico, USA. rehman@salud.unm.edu

World Neurosurgery
|October 12, 2010
PubMed

Insights

Juvenile Paget disease (JPD) is a rare disorder. This report details the first case of JPD with bilateral giant carotid artery aneurysms, successfully treated with bypass and occlusion.

Area of Science:

  • Vascular Surgery
  • Genetics
  • Neurology

Background:

  • Juvenile Paget disease (JPD) is a rare genetic disorder affecting bone, immune, and vascular systems.
  • This report presents the first documented association of JPD with bilateral giant cavernous carotid artery aneurysms in a pediatric patient.

Observation:

  • A child with JPD presented with abducens nerve palsy.
  • Imaging revealed bilateral giant cavernous carotid artery aneurysms.

Findings:

  • The patient underwent successful bilateral superficial temporal artery to middle cerebral artery bypass and endovascular carotid artery occlusion.
  • The patient experienced an event-free recovery with no new neurological deficits.

Implications:

  • This case highlights a previously unreported association between JPD and giant cavernous carotid aneurysms.
  • Optimal management strategies for this rare subgroup require further investigation.
  • Understanding JPD pathophysiology is crucial for managing associated vascular complications.
Abstract

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Arteries of the Head and Neck01:26

Arteries of the Head and Neck

The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
The Arch of Aorta01:10

The Arch of Aorta

The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...