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Published on: October 20, 2017
Floating carotid thrombus treated by intravenous heparin and endarterectomy
Fabrizio Sallustio1, Silvia Di Legge, Simone Marziali
1Stroke Unit, Department of Neuroscience, University of Tor Vergata, Rome, Italy. fabriziosallustio@libero.it
Insights
Atherosclerotic stroke poses a high risk of worsening and recurrence. This case highlights the challenges in managing ischemic stroke caused by internal carotid artery thromboembolism.
Area of Science:
- Neurology
- Vascular Medicine
- Cardiovascular Research
Background:
- Ischemic stroke, particularly atherosclerotic subtypes, presents significant risks for acute worsening and recurrence.
- High-risk factors include plaque rupture, thrombus formation, propagation, vessel occlusion, and distal embolism.
- Management strategies like emergent endarterectomy or anticoagulation followed by delayed endarterectomy remain controversial.
Observation:
- This report details a patient experiencing an ischemic stroke.
- The stroke was attributed to thromboembolism originating from an ulcerated plaque with a floating thrombus.
- The affected artery was the internal carotid artery (ICA).
Findings:
- The patient's ischemic stroke was caused by thromboembolism from an internal carotid artery ulcerated plaque with a floating thrombus.
- The case involves a discussion regarding the controversial application of heparin therapy.
Implications:
- This case underscores the complexities in treating acute ischemic stroke secondary to internal carotid artery disease.
- It prompts further discussion on the efficacy and risks of anticoagulation, such as heparin, in specific thromboembolic stroke scenarios.
- Understanding these mechanisms is crucial for refining acute stroke management protocols and improving patient outcomes.
Abstract:
Among different subtypes of ischemic stroke, atherosclerotic stroke carries the greatest risk (30%) of worsening and recurrence during the acute phase of hospitalization with a 7.9% risk ≤ 30 days. Causes of this high risk include plaque rupture leading to thrombus formation, thrombus propagation with consequent vessel occlusion, and distal embolism. In this context, emergent endarterectomy or anticoagulation, followed by deferred endarterectomy, are both controversial. We report a patient with an ischemic stroke caused by thromboembolism from an ulcerated plaque with floating thrombus of the internal carotid artery (ICA). A controversial use of heparin is discussed.
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