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In Vitro Method to Control Concentrations of Halogenated Gases in Cultured Alveolar Epithelial Cells
Published on: October 23, 2018
Inhalation anaesthetics and climate change
M P Sulbaek Andersen1, S P Sander, O J Nielsen
1Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Mail Stop 183-901, Pasadena, CA 91109, USA. mads@sulbaek.dk
Inhalation anesthetics like isoflurane, desflurane, and sevoflurane significantly contribute to climate change. Their global warming potentials (GWPs) are substantial, comparable to emissions from power plants or cars.
Area of Science:
- Environmental Science
- Atmospheric Chemistry
- Climate Change Research
Background:
- Rising atmospheric CO2 is a primary driver of climate change, but numerous other agents contribute to radiative forcing.
- Inhalation anesthetics such as isoflurane, desflurane, and sevoflurane are emitted during medical procedures and impact climate.
- Quantifying their climate impact requires understanding their infrared absorption properties and atmospheric lifetimes.
Purpose of the Study:
- To quantitatively assess the climate impact of common inhalation anesthetics.
- To determine the radiative forcing contribution of isoflurane, desflurane, and sevoflurane.
- To calculate the Global Warming Potentials (GWPs) for these anesthetic agents.
Main Methods:
- Infrared (IR) spectra of isoflurane, desflurane, and sevoflurane were measured.
- Calculations were performed to determine their radiative forcing, considering wavelength-dependent absorption.
- Global Warming Potentials (GWPs) were established for a 100-year time horizon.
Main Results:
- Radiative efficiencies were determined: 0.453 W m(-2) ppb(-1) for isoflurane, 0.469 W m(-2) ppb(-1) for desflurane, and 0.351 W m(-2) ppb(-1) for sevoflurane.
- 100-year GWPs were calculated: 510 for isoflurane, 1620 for desflurane, and 210 for sevoflurane.
- These values highlight significant climate impacts per anesthetic agent.
Conclusions:
- The average climate impact of one anesthetic procedure is equivalent to approximately 22 kg of CO2.
- Global emissions of these anesthetics have a climate impact comparable to CO2 emissions from a coal-fired power plant or one million cars.
- Reducing anesthetic emissions is crucial for mitigating climate change.
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