Alpha-receptor-mediated modulation of 3H-noradrenaline release from rat brain cortex synaptosomes

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GPCRs Regulate Adenylyl Cylase Activity

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Drugs Acting on Autonomic Ganglia: Stimulants


Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating sympathetic or...
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Adrenergic Neurons: Neurotransmission

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Adrenergic Receptors: β Subtype

β-adrenoceptors have varied sensitivities towards adrenaline, noradrenaline, and isoprenaline. The order of agonist potency is as follows:
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Adrenergic Antagonists: Pharmacological Actions of ɑ-Receptor Blockers

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