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Updated: Jun 8, 2026

A Minimally Invasive Model of Aortic Stenosis in Swine
Published on: October 20, 2023
[Percutaneous treatment of aortic stenosis]
Tolga Aksu1, Uygar Cağdaş Yüksel, Murat Tuzcu
1Department of Cardiology, Türkiye Yüksek İhtisas Heart-Education and Research Hospital, Ankara, Turkey. aksutolga@gmail.com
Insights
Transcatheter aortic valve implantation offers a promising treatment for severe aortic stenosis in patients ineligible for surgery. This minimally invasive procedure has shown significant technological advancements and positive outcomes.
Area of Science:
- Cardiology
- Interventional Cardiology
- Structural Heart Disease
Context:
- Aortic stenosis is a growing global health concern, particularly in aging populations.
- It is the third leading cause of structural heart disease in industrialized nations.
- High surgical risk in elderly patients with comorbidities limits traditional treatment options.
Purpose:
- To review the evolution of transcatheter aortic valve implantation (TAVI).
- To provide insights into the future clinical application of TAVI for severe aortic stenosis.
Summary:
- Balloon aortic valvuloplasty shows unsatisfactory long-term results.
- Percutaneous aortic prosthetic valve implantation (TAVI) has emerged as a viable alternative.
- Since its inception in 2002, TAVI technology has significantly advanced, demonstrating promising results.
Impact:
- TAVI provides a crucial treatment option for high-risk surgical patients with severe aortic stenosis.
- Technological improvements are enhancing the efficacy and safety of TAVI procedures.
- This review highlights the expanding role of TAVI in managing aortic stenosis.
Abstract:
Aortic stenosis has emerged as a global pandemic with the ageing population and has become the third leading cause of structural heart disease after hypertension and coronary artery disease in industrialized countries. Older age and presence of serious comorbid conditions make surgery prohibitively risky in a large group of patients. The long-term results of balloon aortic valvuloplasty have been unsatisfactory, limiting the use of this procedure to only palliation or as a bridge to surgery. Percutaneous aortic prosthetic valve implantation has emerged as a new treatment modality for patients who are not eligible for surgery. After the first successful human application in 2002, transcatheter aortic valve implantation has undergone dramatic technologic improvements, yielding highly promising results. This review presents an outline on the ongoing evolution of transcatheter aortic valve implantation in an attempt to provide insight into its future use in the clinical management of severe aortic stenosis.
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