Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Increased Intracranial Pressure l: Introduction

Increased Intracranial Pressure l: Introduction

Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...

Increased Intracranial Pressure ll: Pathophysiology

Increased Intracranial Pressure ll: Pathophysiology

Increased intracranial pressure (ICP) refers to a potentially life-threatening rise in pressure inside the skull. This usually happens when there is a major change in the volume of brain tissue, blood, or cerebrospinal fluid (CSF) — the three components inside the skull. According to the Monro-Kellie doctrine, if the volume of one component increases, the volumes of the other components must decrease to maintain normal pressure. If this does not happen, ICP rises.The process often begins with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A prospective, randomized study comparing the effects of preservative-free latanoprost and preserved latanoprost eyedrops on MMP-9 expression and ocular surface disease index in glaucoma patients.

Japanese journal of ophthalmology·2026

Same author

Long-term Persistent Angle Closure and Anatomic Changes after Laser Iridotomy in Suspected Primary Angle-Closure.

Ophthalmology·2025

Same author

Elevated lamina cribrosa-sclera interface stress in glaucomatous eyes with optic disc haemorrhage.

The British journal of ophthalmology·2025

Same author

Relationship Between Periodontitis and Open Angle Glaucoma: The Korea National Health and Nutrition Examination Survey.

Journal of glaucoma·2025

Same author

Asymmetric stress distribution on lamina cribrosa in glaucoma patients with high myopia.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2025

Same author

Effects of Stress and Strain on the Optic Nerve Head on the Progression of Glaucoma.

Journal of glaucoma·2024

Search research articles

Related Experiment Video

Updated: Jun 8, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

Changes in intraocular pressure during strabismus surgery.

Chungkwon Yoo¹, Mun Hee Chang, Jong-Suk Song

¹Department of Ophthalmology, Korea University College of Medicine, Ansan, Republic of Korea.

Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie

|October 12, 2010

Summary

This summary is machine-generated.

Intraocular pressure (IOP) changes after detaching eye muscles during exotropia surgery may indicate muscle contracture. This finding could offer a new way to assess muscle tightness in strabismus patients.

More Related Videos

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Related Experiment Videos

Last Updated: Jun 8, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Area of Science:

Ophthalmology
Surgical Research
Strabismus Surgery

Background:

Exotropia surgery involves muscle recession, and assessing muscle contracture is crucial.
Intraocular pressure (IOP) changes during surgery are not fully understood in relation to muscle status.

Purpose of the Study:

To investigate if intraocular pressure (IOP) alterations after lateral rectus muscle detachment during exotropia surgery correlate with muscle contracture.
To explore potential surrogate markers for muscle contracture in strabismus surgery.

Main Methods:

A prospective study involving 60 eyes of 31 patients undergoing lateral rectus recession for exotropia.
Intraocular pressure (IOP) was measured using a Tono-pen XL before and immediately after detaching the lateral rectus muscle.
Correlations between IOP changes and clinical variables (age, disease duration, exodeviation amount, etc.) were analyzed.

Main Results:

A significant IOP decline was observed after muscle detachment (from 16.3 to 10.8 mm Hg).
The reduction in IOP immediately after muscle detachment positively correlated with constant exodeviation.
No significant correlation was found between IOP changes and age, disease duration, or tendon width.

Conclusions:

Changes in intraocular pressure (IOP) following extraocular muscle detachment during strabismus surgery may serve as a surrogate parameter for muscle contracture.
This IOP monitoring could provide valuable insights into muscle status during exotropia correction.