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Updated: Jan 26, 2026

Three-Dimensional Reconstruction of Orbital Fractures

Three-Dimensional Reconstruction of Orbital Fractures

Published on: May 16, 2025

Retinoblastoma: postenucleation orbital recurrence.

Muhammad Arif¹, Ziaul Islam

¹Department of Ophthalmology, KUST Institute of Medical Sciences, Kohat, Pakistan. arifmdn@yahoo.com

Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie

|October 12, 2010

Summary

This study highlights poor follow-up in retinoblastoma patients, leading to orbital recurrence. Identifying clinicopathological factors is crucial for early detection and better outcomes in children with retinoblastoma.

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Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

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Published on: August 4, 2011

Area of Science:

Ophthalmology
Pediatric Oncology

Background:

Retinoblastoma is a common intraocular malignancy in children.
Postenucleation orbital recurrence is a significant concern impacting patient prognosis.

Purpose of the Study:

To identify clinicopathological variables associated with postenucleation orbital recurrence in retinoblastoma.
To emphasize the importance of diligent follow-up to preempt orbital recurrence.

Main Methods:

Retrospective, case-controlled, longitudinal study of 176 children with retinoblastoma.
Analysis of patient charts to identify cases of orbital recurrence after primary enucleation.

Main Results:

Orbital recurrence was diagnosed in 31 patients, with a mean age of 4.09 years.
The majority of recurrences (90.4%) occurred within 1-12 months post-enucleation.
Inadequate documentation of histopathology (26%) and follow-up (9.6%) was noted.

Conclusions:

Failure to identify key clinical and pathological parameters contributes to poor outcomes.
Insufficient follow-up and negligence exacerbate the challenges in managing retinoblastoma, leading to significant patient suffering.