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Idiopathic bladder hyperactivity treated with Ditropan (oxybutynin chloride)
1Department of Urology, Semmelweis University Medical School, Budapest, Hungary.
International Urology and Nephrology
|January 1, 1990
Summary
Ditropan (oxybutynin chloride) effectively treated patients with hyperactive bladder by reducing urination frequency and urgency. The medication also increased bladder capacity, with mild dry mouth as the main side effect.
Area of Science:
- Urology
- Pharmacology
Background:
- Idiopathic hyperactive bladder is characterized by involuntary bladder contractions.
- Urinary frequency, urgency, and incontinence are common symptoms.
Purpose of the Study:
- To evaluate the efficacy of Ditropan (oxybutynin chloride) in patients with idiopathic hyperactive bladder.
- To assess the effects of oxybutynin chloride on bladder capacity and voiding parameters.
Main Methods:
- A study involving 25 patients diagnosed with idiopathic hyperactive bladder.
- Administration of Ditropan (oxybutynin chloride) and subsequent control cystometry.
Main Results:
- Oxybutynin chloride significantly reduced voiding frequency and abolished urinary urgency.
- Bladder capacity was significantly increased as confirmed by cystometry.
- Oral dryness was observed as a tolerable side effect in patients.
Conclusions:
- Ditropan (oxybutynin chloride) is an effective treatment for idiopathic hyperactive bladder.
- The medication improves bladder function and patient-reported symptoms.
- Oxybutynin chloride presents a favorable safety profile with manageable side effects.