Related Experiment Video
Updated: Jun 8, 2026

Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle
Published on: August 30, 2021
Menstrual cycles are influenced by sunshine.
Konstantin V Danilenko1, Oksana Y Sergeeva, Evgeniy G Verevkin
1Institute of Internal Medicine, Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk, Russia. kvdani@mail.ru
Seasonal changes significantly impact ovarian function in women. Increased sunshine in summer correlates with higher ovulation rates and shorter menstrual cycles, indicating environmental influences on reproductive health.
Area of Science:
- Reproductive Endocrinology
- Chronobiology
- Human Physiology
Background:
- Investigates the influence of seasonal variations and meteorological factors on the female reproductive system.
- Examines ovarian-menstrual function in women residing in a temperate continental climate.
Purpose of the Study:
- To determine the effect of seasons and meteorological variables on ovarian-menstrual function.
- To assess seasonal differences in reproductive hormone levels, ovarian follicle size, and ovulation frequency.
Main Methods:
- Longitudinal study of 129 women in Novosibirsk, Russia, over a decade (1999-2008).
- Cross-sectional analysis of 38 women in winter and summer (2006-2009).
- Measured serum FSH, LH, prolactin, ovarian follicle size via ultrasound, and ovulation occurrence; correlated with meteorological data.
Main Results:
- Summer was associated with increased FSH, larger follicle size, higher ovulation rates (97% vs. 71%), and shorter cycles compared to winter.
- Increased sunshine duration 2-3 days prior to ovulation correlated with shorter menstrual cycle length.
- LH, prolactin levels, temperature, and atmospheric pressure were not significant predictors.
Conclusions:
- Ovarian activity is enhanced during summer in women at temperate latitudes.
- Sunshine is identified as a key environmental factor influencing menstrual cycle length and regularity.
Related Concept Videos
Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
The Menstrual Cycle
The menstrual phase occurs from days 1 to 5 and involves the shedding of the stratum functionalis, as a uterine...
Hormonal Control of the Ovarian Cycle
Before puberty, the hypothalamus releases GnRH in a low frequency, low amplitude pulsatile manner. This along with the immature hypothalamic-pituitary-gonadal axis activity, results in low estrogen levels and the absence of a fully functional ovarian cycle. At puberty, GnRH secretion increases in both frequency and...
Menses Phase
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
Ovarian Cycle
Secretory Phase
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
