Infectious causes of appendicitis

Laura W Lamps1

  • 1Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. lampslauraw@uams.edu

Insights

This review explores infectious appendicitis, covering bacterial, viral, fungal, and parasitic causes. It details pathologic features and diagnostic methods for these diverse appendix infections.

Area of Science:

  • Gastroenterology
  • Pathology
  • Infectious Diseases

Background:

  • Inflamed appendix pathology involves diverse infectious entities.
  • Appendix involvement can be primary or secondary to gastrointestinal spread.
  • Diagnosis may require extensive evaluation due to nonspecific findings.

Purpose of the Study:

  • To review the pathologic features of infectious agents affecting the appendix.
  • To discuss diagnostic techniques and clinical significance of appendiceal infections.

Main Methods:

  • Literature review of infectious diseases impacting the appendix.
  • Analysis of pathologic and histologic findings.
  • Discussion of clinical context and diagnostic approaches.

Main Results:

  • Identified bacterial, viral, fungal, and parasitic infections of the appendix.
  • Detailed specific pathogens like adenovirus, cytomegalovirus, Yersinia, Actinomyces, Mycobacterium, Histoplasma, Enterobius vermicularis, Schistosomiasis, and Strongyloides stercoralis.
  • Highlighted diagnostic challenges and ancillary techniques.

Conclusions:

  • Infectious appendicitis presents a broad spectrum of pathologic findings.
  • Understanding diverse pathogens is crucial for accurate diagnosis and management.
  • Ancillary diagnostic methods aid in identifying specific infectious causes.

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