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Updated: Jun 8, 2026

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On the isomerisation of cefozopran in solution

Shu-Yu Liu1, Dou-Sheng Zhang, Chang-Qin Hu

  • 1Shanghai University of Engineering Science, Shanghai 201620, People's Republic of China.

European Journal of Medicinal Chemistry
|October 13, 2010
PubMed
Summary

Cefozopran exists in two configurations, with the cis-isomer exhibiting superior antimicrobial activity compared to the trans-isomer. This study elucidates their structures and stability, offering insights into cephalosporin configuration-activity relationships.

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