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Related Experiment Video

Updated: Jun 8, 2026

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System

Modeling Breast Cancer in Human Breast Tissue using a Microphysiological System

Published on: April 23, 2021

Rare benign breast tumor.

Jaime Román-Díaz¹, Diógenes Alayón-Laguer, Matos Fernández Nelson

¹VA Caribbean Healthcare System, Hematology-Oncology program, 10 Calle Casia, San Juan, Puerto Rico 00921. romanjaime@hotmail.com

Boletin De La Asociacion Medica De Puerto Rico

|October 14, 2010

Summary

This summary is machine-generated.

A benign spindle cell tumor, Breast Myofibroblastoma, was incidentally found during mammography. Recognizing its benign nature is crucial to avoid unnecessary surgical procedures.

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Area of Science:

Oncology
Pathology
Radiology

Background:

Breast Myofibroblastoma is a rare benign mesenchymal neoplasm.
Incidental findings on routine mammography require careful characterization.

Observation:

A case of incidental Breast Myofibroblastoma discovered during routine mammography is presented.
The tumor exhibited a fascicular arrangement with hyalinized collagen.

Findings:

Immunohistochemistry showed variable reactivity to desmin, vimentin, smooth muscle actin, and CD 34.
The neoplasm was non-reactive to cytokeratins and S-100, distinguishing it from myoepitheliomas.

Implications:

Accurate diagnosis of Breast Myofibroblastoma is essential to prevent overtreatment.
Understanding the benign characteristics can guide conservative management strategies.