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Updated: Jun 8, 2026

Optical Control of Living Cells Electrical Activity by Conjugated Polymers
Published on: January 28, 2016
Two-photon excited fluorescence of a conjugated polyelectrolyte and its application in cell imaging
Abstract:
The two-photon excited fluorescence of a conjugated polyelectrolyte (CPE), PPESO3, was studied in methanol and in water. The photophysical and amplified quenching properties of the CPE observed under two-photon excitation were comparable to the results obtained under one-photon excited conditions. Two-photon fluorescence microscopy performed with PPESO3-coated silica nanoparticles in HeLa cells provided images with significantly improved resolution compared to one-photon microscopy, demonstrating the utility of the CPE as a fluorescent probe in two-photon fluorescence cell imaging.
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