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Updated: Jun 8, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair

A New Murine Model of Endovascular Aortic Aneurysm Repair

Published on: July 7, 2013

Aortic neck angulations decrease during and after endovascular aneurysm repair.

Jasper W van Keulen¹, Frans L Moll, Jeroen Arts

¹Department of Vascular Surgery, University Medical Center Utrecht, The Netherlands.

Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists

|October 14, 2010

Summary

Aortic neck angles decrease significantly after endovascular aneurysm repair (EVAR) and continue to decrease during follow-up. This angle change impacts stent-graft sealing and long-term EVAR outcomes.

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Area of Science:

Vascular Surgery
Medical Imaging
Biomedical Engineering

Background:

Endovascular aneurysm repair (EVAR) relies on proper stent-graft sealing and fixation.
Aortic neck angulation is a critical factor influencing EVAR success.
Changes in aortic angulation post-EVAR may affect long-term outcomes.

Purpose of the Study:

To determine if suprarenal and infrarenal aortic neck angles change after EVAR.
To assess if these angle changes persist during long-term follow-up.
To understand the implications of angle changes on EVAR sealing and fixation.

Main Methods:

Retrospective analysis of 43 EVAR patients' computed tomographic angiography (CTA) data.
Measurement of suprarenal and infrarenal aortic angles using a 3D centerline method.
Statistical analysis including repeated measures and post-hoc tests to evaluate changes over time.

Main Results:

Significant decrease in mean suprarenal angulation from 28° preoperatively to 16° at 3-year follow-up.
Significant decrease in mean infrarenal angulation from 50° preoperatively to 36° at 3-year follow-up.
Both angle reductions were statistically significant (p<0.01) at all measured time points.

Conclusions:

Aortic neck angles decrease immediately after EVAR.
These angles continue to decrease during the years following EVAR.
The observed angulation changes are significant and may impact EVAR efficacy.