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Updated: Jun 8, 2026

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Published on: September 8, 2023

Revisiting the microtrabecular lattice.

James S Clegg¹

¹University of California, Davis, 94923, USA. jsclegg@ucdavis.edu

Cell Biology International

|October 14, 2010

Summary

This summary is machine-generated.

The microtrabecular lattice (MTL), once dismissed as an artifact, is proposed as a dynamic fundamental structure within eukaryotic cells. This reconsideration suggests MTL exists, but is more fluid than early electron microscopy images indicated.

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Area of Science:

Cell Biology
Cytoskeletal Dynamics

Background:

The microtrabecular lattice (MTL) was initially described by Keith Porter in the 1970s-1980s.
MTL was largely disregarded by the scientific community as an artifact of electron microscopy.

Purpose of the Study:

To re-evaluate the existence and nature of the microtrabecular lattice (MTL) in eukaryotic cells.
To propose MTL as a fundamental, dynamic cytoplasmic structure.

Main Methods:

Reconsideration of historical electron microscopy data.
Theoretical analysis of cytoplasmic organization.

Main Results:

The study argues for the potential existence of a structure akin to the MTL.
The proposed MTL is significantly more dynamic than previously depicted.

Conclusions:

The microtrabecular lattice (MTL) may represent a real, dynamic component of the eukaryotic cytoplasm.
Further research is needed to characterize the dynamic nature of MTL.